Hauptinhalt Zehn ausgewählte Publikationen
Ganjam, G.K., Terpolilli, N.A., Diemert, S., Eisenbach, I., Hoffmann, L., Reuther, C., Herden, C., Roth, J., Plesnila, N., Culmsee, C.Cylindromatosis mediates neuronal cell death in vitro and in vivo. Cell Death and Differentiation, 2018 Jan 19. doi: 10.1038/s41418-017-0046-7.
Rehklau, K., Hoffmann, L., Gurniak, C.B., Ott, M., Witke, W., Scorrano, L., Culmsee, C., Rust, M.B.Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission. Cell Death and Disease, 2017 8(10):e3063. doi: 10.1038/cddis.2017.448.
Neitemeier, S., Jelinek, A., Laino, V., Hoffmann, L., Eisenbach, I., Eying, R., Ganjam, G.K., Dolga, A.M., Oppermann, S., Culmsee, C.BID links ferroptosis to mitochondrial cell death pathways. Redox Biology, 2017, 12:558-570. doi: 10.1016/j.redox.2017.03.007.
Neitemeier, S., Dolga, A.M., Honrath, B., Karuppagounder, S.S., Alim, I., Ratan, R.R., Culmsee, CInhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis. Cell Death and Disease, 2016, 7:e2214. doi: 10.1038/cddis.2016.107.
Richter, M., Vidovic, N., Honrath, B., Mahavadi, P., Dodel, R., Dolga, A.M., Culmsee, C.Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death. Cell Death and Differentiation, 2016, 23(5):814-827. doi: 10.1038/cdd.2015.146.
Dolga, A.M., Netter, M.F., Perocchi, F., Doti, N., Meissner, L., Tobaben, S., Grohm, J., Zischka, H., Plesnila, N., Decher, N., Culmsee, C.Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction. Journal of Biological Chemistry, 2013, 288(15):10792-10804. doi: 10.1074/jbc.M113.453522.
Grohm, J., Kim, S.W., Mamrak, U., Tobaben, S., Cassidy-Stone, A., Nunnari, J., Plesnila, N., Culmsee C.Inhibition of Drp1 provides neuroprotection in vitro and in vivo. Cell Death and Differentiation, 2012, 19(9):1446-1458. doi: 10.1038/cdd.2012.18.
Tobaben S, Grohm J, Seiler A, Conrad M, Plesnila N, Culmsee C.Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons. Cell Death Differ. 2011 Feb;18(2):282-292. doi: 10.1038/cdd.2010.92.
Landshamer, S., Hoehn, M., Barth, N., Duvezin-Caubet, S., Schwake, G., Tobaben, S., Kazhdan, I., Becattini, B., Zahler, S., Vollmar, A., Pellecchia, M., Reichert, A., Plesnila, N., Wagner, E., Culmsee C.Bid-induced release of AIF from mitochondria causes immediate neuronal cell death. Cell Death and Differentiation, 2008, 15(10):1553-1563. doi: 10.1038/cdd.2008.78.
Culmsee, C., Zhu, C., Landshamer, S., Becattini, B., Wagner, E., Pellecchia, M., Blomgren, K., Plesnila, N.Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia . Journal of Neuroscience, 2005, 25(44):10262-10272.
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