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Prof. Dr. Dominik Oliver

Research interests

Our research aims at understanding the role of ion channels and the transporter-related membrane protein prestin (SLC26A5) in the cellular physiology of auditory sensory hair cells. Closely related to this topic we address the molecular and structural principles underlying the function and regulation of these and related proteins.
Another major research focus lies on intracellular signaling pathways mediated by phosphoinositide concentration dynamics. Here we are mainly interested in the role of specific phospholipid species in regulating ion channel activity and subcellular actin dynamics.
In terms of methods, our lab has extensive expertise in cellular electrophysiology (patch clamp), live-cell fluorescence microscopy (confocal, TIRF, and others), use and development of genetically encoded molecular sensors and tools for manipulation of intracellular signalling pathways, as well as molecular biology.